Endometrial cancer fertility preservation

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Oncolog-Hematolog Nr. Keywords oncofertility, cryopreservation, survival, fertilization Rezumat Oncofertilitatea este o nouă ramură a medicinei, dezvoltată din nevoia de a trata cel mai frecvent efect secundar pe termen lung al tratamentului oncologic — infertilitatea.

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Oncofertilitatea — o şansă la o viaţă normală pentru tinerele supravieţuitoare ale cancerului Endometrial cancer fertility preservation. Oncofertilitatea — o şansă la o viaţă normală pentru tinerele supravieţuitoare ale cancerului Young survivors who have not completed their family yet have now a chance given by oncofertility procedures. The main strategies used in preserving fertility in oncology patients are: ovarian stimulation followed by cryopreservation of oocytes, transposition of the ovaries before radiotherapy, cryopreservation and transplantation of ovarian tissue, and the administration of gonadotropin-releasing hormone GnRH agonists, each technique being individua­lized for each patient. Keywords oncofertility, cryopreservation, survival, fertilization Rezumat Oncofertilitatea este o nouă ramură a medicinei, dezvoltată din nevoia de a trata cel mai frecvent efect secundar pe termen lung al tratamentului oncologic — infertilitatea.

Fertility Preservation in Patients with Endometrial Cancer paraziti tratamentul tractului gastrointestinal

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Young survivors who have not completed their family yet have now a chance given by oncofertility procedures. The main strategies used in preserving fertility in oncology patients are: ovarian stimulation followed by cryopreservation of oocytes, transposition of the ovaries before radiotherapy, cryopreservation and transplantation of ovarian tissue, and the administration of gonadotropin-releasing hormone GnRH agonists, each technique being individua­lized for each patient.

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Markerii tumorali — Tot ce trebuie să ştii Furthermore, the surgical treatment by TNM stages was achieved, measuring the survival rate after five years of follow-up. Most of the patients with malignant disease were multiparous Moreover, from menopausal patients, the higher prevalence was seen at the group between 45 and 55 years old, not being dependent on the earlier appearance. The highest incidence of gynecological pathology was seen in women with polycystic ovaries i. Regarding serum CA tumoral marker, higher values were noticed in the majority of patients The highest prevalence of surgical treatment in the first endometrial cancer tumor markers second stages was represented by total hysterectomy with bilateral anexectomy, omentectomy and peritoneal lavage, and for the third and fourth stages, endometrial cancer tumor markers hysterectomy, bilateral anexectomy, omentectomy, peritonectomy and lymphadenectomy, with a better survival rate at five years seen in patients under the age of 30 years old.

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The endometrial regeneration frontiers: from mechanisms to applications in regenerative medicine Cornelia Amalinei, Ioana Pavaleanu, Adriana Grigoras, Irina-Draga Caruntu, Simona Eliza Giusca, Elena Roxana Avadanei, Ludmila Lozneanu, Raluca Anca Balan The endometrium is a unique and remarkable tissue characterized by a constant regeneration activity and this has been speculative for scientists, regarding endometrial cancer fertility preservation mechanism, regulatory factors, and their significance for fertility and endometrial pathology. Relatively recent scientific progresses due to genomics, proteomics, and transcriptomics have changed the knowledge in respect with endometrial regeneration and uterine-derived diseases. Our review is designed to highlight the recent progresses in understanding the endometrial physiology and its alterations involvement in uterine-derived diseases, addressing the current paradigm regarding endometrial regeneration, based on endometrial regenerative cells. In an attempt to explain the complex process of endometrial regeneration, different mechanisms have been proposed during time, from proliferation of basal glandular cells, to mesenchymal-epithelial transition, and lately to differentiation of stromal cells, based on endometrial regenerative cells or stem cells.

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